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Skin aging and DNA research

What is DNA damage?

The human body is generated based on the blueprint known as DNA. The skin, a part of the body, is programmed into the future by the very same blueprint. If we could keep our DNA flawless and undamaged, so too would we keep our skin healthy and beautiful. Yet DNA is constantly being damaged over time by adverse factors such as inflammation and stress. The two main causes of DNA damage are UV rays and reactive oxygen species (free radicals). When DNA is damaged, it fails to correctly transmit the genetic information for normal skin function at cellular and tissue levels. This is the main cause of skin aging.

DNA damage

Focusing on the DNA repair system

The cells in our bodies are equipped with a DNA repair system that rapidly restores damaged DNA to its original condition. Yet DNA damages gradually accumulate over months and years, while our capacity for repair deteriorates as we age. Two key steps for keeping skin in a youthful condition are to use UV blocks and antioxidants to prevent DNA damage induced by UV and reactive oxygen species. These steps alone, however, will only partly solve the problem. We also need to enhance the skin’s capacity to repair DNA damage by boosting the repair mechanisms at the cellular level. Kanebo Cosmetics has been a forerunner in this area for many years, actively promoting fundamental dermatological research with Japanese universities specialized in this field of research. Through our research we have become worldwide pioneers of skincare with DNA repair technologies effective in maintaining the optimum skin condition into the future.

Changes in DNA repair capacity due to aging

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